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The dipstick does not measure beta-hydroxybutyrate, the most abundant of the physiological ketone bodies; the nitroprusside reagent just reacts with acetoacetate and acetone. 1. Source of Scientific Chemistry. Edited by CA Burtis, ER Ashwood. Philadelphia, WB Saunders Co. 1999 2. Vassault A, Bonnefont JP, Specola N, et al: Lactate, pyruvate, and ketone bodies.
Edited by F Hommes. New York City, Wiley-Liss, 1991 3. Bonnefont JP, Specola NB, Vassault A, et al: The fasting test in paediatrics: application to the diagnosis of pathological hypo- and hyperketotic states. Eur J Pediatr 1990; 150:80 -85.
An introduction to Beta-Hydroxybutyrate The Stanbio Chemistry Liqui, Color Beta-Hydroxybutyrate (B-HB) reagent is utilized to find ketones to identify clients struggling with diabetic ketoacidosis, amongst many other scientific applications. Beta-hydroxybutyrate is the finest test for keeping track of ketosis Beta-Hydroxybutyrate is one of the most predominate ketone present throughout DKA and trends with a client's medical status.
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Our Beta-Hydroxybutyrate reagent is used by over 1,100 medical facilities in the U.S.A. and can be worked on an open channel of a lab analyzer. In addition, Beta-Hydroxybutyrate can be used to scientifically diagnose and keep track of the disease status or severity of alcoholism, glycogen storage disease, high fat/low carb diet plans, pregnancy, alkalosis, consumption of isopropyl alcohol, and salicylate poisoning.
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When the body senses glucose is not readily available, fat is broken down instead. As fats are broken down, acids called ketones build up in the blood and urine. Ketones are harmful in high levels. This condition is called ketoacidosis. Blood sugar levels rise (generally higher than 200 mg/d, L) since the liver makes glucose to try to combat the problem.
Symptoms can include quick deep breathing, dry skin and mouth, flushed face, fruity smelling breath, queasiness, vomiting and stomach discomfort. Other symptoms that can occur are; stomach discomfort, breathing problem while resting, decreased appetite, reduced awareness, muscle tightness and aches, dulled senses that may aggravate to a coma and regular urination and thirst that lasts for a day or more.
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Ketones (like glucose) can be evaluated or kept an eye on in either urine or blood. Numerous health centers still utilize the nitroprusside method for verifying ketoacidosis. The nitroprusside urine technique is efficient at offering qualitative evaluation of ketosis and ketoacidosis by spotting both acetoacetate and acetone. However, nitroprusside approaches do not identify Beta-Hydroxybutyrate.